The D3football.com Top 25, entering the 2021 season. This is the 18th season of the D3football.com Top 25.
| Rank | School (No. 1 votes) | W-L | 2019 | Points |
| 1 | Mary Hardin-Baylor (10) | 5-0 | 12-1 | 595 |
| 2 | Mount Union (6) | 4-0 | 11-1 | 580 |
| 3 | North Central (Ill.) (4) | 0-0 | 14-1 | 566 |
| 4 | UW-Whitewater (1) | 0-0 | 13-2 | 565 |
| 5 | Wheaton (Ill.) (4) | 0-0 | 12-1 | 534 |
| 6 | St. John's | 0-0 | 12-2 | 458 |
| 7 | Hardin-Simmons | 4-1 | 8-2 | 438 |
| 8 | Salisbury | 2-0 | 11-1 | 397 |
| 9 | UW-Oshkosh | 0-0 | 8-3 | 382 |
| 10 | Linfield | 0-0 | 8-2 | 336 |
| 11 | John Carroll | 2-1 | 9-1 | 322 |
| 12 | Delaware Valley | 0-0 | 11-2 | 318 |
| 13 | Muhlenberg | 0-0 | 13-1 | 279 |
| 14 | Central | 2-0 | 10-2 | 207 |
| 15 | Union | 0-0 | 11-1 | 202 |
| 16 | Bethel | 0-0 | 8-2 | 200 |
| 17 | Randolph-Macon | 5-0 | 9-2 | 184 |
| 18 | Wartburg | 0-0 | 10-2 | 181 |
| 19 | Washington and Jefferson | 3-1 | 8-3 | 173 |
| 20 | Westminster (Pa.) | 5-0 | 8-3 | 151 |
| 21 | Chapman | 0-0 | 10-1 | 143 |
| 22 | Brockport | 0-0 | 9-3 | 131 |
| 23 | Aurora | 3-0 | 9-2 | 120 |
| 24 | Heidelberg | 4-1 | 6-4 | 103 |
| 25 | Berry | 4-0 | 9-2 | 75 |
Others receiving votes: Whitworth 71; Bridgewater (Va.) 45; Ithaca 45; Illinois Wesleyan 41; Johns Hopkins 41; UW-La Crosse 38; Case Western Reserve 38; Hanover 32; Wabash 30; Redlands 26; Susquehanna 22; Montclair State 13; Hendrix 10; Hope 9; Millikin 5; UW-Platteville 4; Western New England 4; Denison 3; Huntingdon 3; East Texas Baptist 3; Stevenson 2; Washington U. 1.
The D3football.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.