Through games of Saturday, Oct. 2, 2010:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | UW-Whitewater (22) | 4-0 | 622 | 1 |
| 2 | Mount Union (3) | 4-0 | 603 | 2 |
| 3 | Wesley | 5-0 | 565 | 3 |
| 4 | St. Thomas | 5-0 | 547 | 4 |
| 5 | Mary Hardin-Baylor | 4-0 | 525 | 5 |
| 6 | Coe | 5-0 | 487 | 6 |
| 7 | North Central (Ill.) | 4-0 | 430 | 8 |
| 8 | Wittenberg | 5-0 | 421 | 7 |
| 9 | Central | 4-1 | 360 | 9 |
| 10 | Thomas More | 4-0 | 356 | 11 |
| 11 | Hardin-Simmons | 4-1 | 348 | 12 |
| 12 | Delaware Valley | 3-1 | 332 | 13 |
| 13 | Ohio Northern | 3-1 | 310 | 8 |
| 14 | Linfield | 2-1 | 301 | 16 |
| 15 | Trine | 4-0 | 293 | 14 |
| 16 | Montclair State | 4-0 | 248 | 17 |
| 17 | UW-Eau Claire | 3-1 | 215 | 18 |
| 18 | Wheaton (Ill.) | 4-0 | 179 | 21 |
| 19 | Wabash | 4-0 | 157 | 20 |
| 20 | St. John Fisher | 5-0 | 136 | 24 |
| 21 | Alfred | 4-0 | 98 | 25 |
| 22 | Cal Lutheran | 2-1 | 97 | 23 |
| 23 | St. John's | 3-2 | 79 | 19 |
| 24 | Randolph-Macon | 5-0 | 78 | 25 |
| 25 | Cortland State | 4-0 | 46 | --- |
Dropped out: No. 15 Willamette, No. 22 Illinois Wesleyan.
Others receiving votes: Hampden-Sydney 44, Wartburg 33, Pacific Lutheran 33, Willamette 30, Case Western Reserve 29, Ursinus 21, Otterbein 18, Franklin 16, Illinois Wesleyan 12, Baldwin-Wallace 9, DePauw 8, UW-Oshkosh 8, Elmhurst 7, Augustana 5, UW-Stevens Point 4, Springfield 4, Millikin 4, UW-Stout 3, Bethel 2, Amherst 2.
The D3football.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.