Through games of Saturday, Sept. 25, 2010:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | UW-Whitewater (22) | 3-0 | 622 | 1 |
| 2 | Mount Union (3) | 3-0 | 603 | 2 |
| 3 | Wesley | 4-0 | 565 | 3 |
| 4 | St. Thomas | 4-0 | 551 | 4 |
| 5 | Mary Hardin-Baylor | 3-0 | 529 | 5 |
| 6 | Coe | 4-0 | 465 | 9 |
| 7 | Wittenberg | 4-0 | 463 | 6 |
| 8 | Ohio Northern | 3-0 | 408 | 10 |
| 9 | Central | 3-1 | 383 | 7 |
| 10 | North Central (Ill.) | 3-0 | 340 | 11 |
| 11 | Thomas More | 3-0 | 337 | 12 |
| 12 | Hardin-Simmons | 3-1 | 324 | 8 |
| 13 | Delaware Valley | 2-1 | 322 | 13 |
| 14 | Trine | 3-0 | 271 | 14 |
| 15 | Willamette | 2-1 | 236 | 15 |
| 16 | Linfield | 1-1 | 215 | 16 |
| 17 | Montclair State | 3-0 | 186 | 19 |
| 18 | UW-Eau Claire | 2-1 | 174 | 17 |
| 19 | St. John's | 3-1 | 158 | 18 |
| 20 | Wabash | 3-0 | 137 | 20 |
| 21 | Wheaton (Ill.) | 3-0 | 122 | 22 |
| 22 | Illinois Wesleyan | 3-0 | 95 | 21 |
| 23 | Cal Lutheran | 1-1 | 77 | 24 |
| 24 | St. John Fisher | 4-0 | 75 | -- |
| 25 | Randolph-Macon | 4-0 | 74 | 25 |
| 25 | Alfred | 3-0 | 74 | 23 |
Dropped out: None.
Others receiving votes: UW-Stevens Point 61, Hampden-Sydney 38, Ursinus 29, Wartburg 27, Case Western Reserve 25, UW-Oshkosh 24, Pacific Lutheran 23, Cortland State 17, DePauw 14, Washington and Jefferson 11, Johns Hopkins 11, Otterbein 9, Bethel 7, Franklin and Marshall 5, Carthage 4, Franklin 3, UW-Stout 3, Elmhurst 2, Baldwin-Wallace 2, Millikin 1.
The D3football.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.