Through games of Saturday, Sept. 11, 2010:
| # | School (1st votes) | Rec. | Pts | Prev. |
| 1 | UW-Whitewater (22) | 2-0 | 622 | 1 |
| 2 | Mount Union (3) | 1-0 | 602 | 2 |
| 3 | Wesley | 2-0 | 567 | 3 |
| 4 | St. Thomas | 2-0 | 553 | 5 |
| 5 | Mary Hardin-Baylor | 1-0 | 511 | 6 |
| 6 | Wittenberg | 2-0 | 499 | 8 |
| 7 | Central | 2-0 | 476 | 7 |
| 8 | Delaware Valley | 2-0 | 415 | 10 |
| 9 | Hardin-Simmons | 2-0 | 399 | 14 |
| 10 | Coe | 2-0 | 373 | 12 |
| 11 | Ohio Northern | 1-0 | 328 | 11 |
| 12 | Thomas More | 1-0 | 301 | 15 |
| 13 | Willamette | 1-1 | 291 | 13 |
| 14 | North Central (Ill.) | 1-0 | 274 | 16 |
| 15 | Cal Lutheran | 1-0 | 247 | 25 |
| 16 | Linfield | 0-1 | 238 | 4 |
| 17 | Trine | 2-0 | 182 | 17 |
| 18 | Otterbein | 1-0 | 158 | 18 |
| 19 | Mississippi College | 2-0 | 138 | 21 |
| 20 | UW-Eau Claire | 2-0 | 137 | -- |
| 21 | St. John's | 1-1 | 127 | 9 |
| 22 | Wabash | 1-0 | 102 | 22 |
| 23 | Montclair State | 1-0 | 101 | 23 |
| 24 | Illinois Wesleyan | 2-0 | 97 | 24 |
| 25 | Alfred | 1-0 | 64 | -- |
Dropped out: No. 19 Johns Hopkins, No. 20 Washington and Jefferson.
Others receiving votes: Wheaton (Ill.) 60, UW-Stevens Point 37, Hampden-Sydney 35, St. John Fisher 27, DePauw 22, Wartburg 19, Randolph-Macon 17, Washington and Jefferson 15, Case Western Reserve 14, Ursinus 13, Johns Hopkins 10, Ithaca 10, UW-Oshkosh 9, Cortland State 7, Salisbury 6, Trinity (Texas) 5, UW-Stout 4, Hobart 4, Huntingdon 3, Bethel 2, Mount St. Joseph 1, Franklin and Marshall 1, Baldwin-Wallace 1.
The D3football.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.