2010 Schedule N.C. Wesleyan
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 7-3 | .700 | 6-1 | .857 | Won 4 | 4-1 | 3-2 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 4 | at Salisbury | L, 13-7 | Final | BX |
| Sep. 11 | at Hampden-Sydney | L, 21-19 | Final | BX BX |
| Sep. 25 | LaGrange | W, 35-24 | Final | BX |
| Oct. 2 | at Ferrum * | W, 24-14 | Final | BX |
| Oct. 9 | Greensboro * | W, 48-12 | Final | |
| Oct. 16 | Christopher Newport * | L, 23-15 | Final | BX RC |
| Oct. 23 | at Maryville (Tenn.) * | W, 34-16 | Final | BX |
| Oct. 30 | Methodist * | W, 56-6 | Final | BX |
| Nov. 6 | at Shenandoah * | W, 38-0 | Final | BX BX RC P P P |
| Nov. 13 | Averett * | W, 28-13 | Final | |
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