2010 Schedule Hardin-Simmons
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 8-2 | .800 | 6-2 | .750 | Lost 1 | 5-0 | 3-2 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 4 | at Whitworth | W, 27-7 | Final | BX BX RC |
| Sep. 11 | Willamette | W, 31-22 | Final | BX BX RC |
| Sep. 18 | Mississippi College * | W, 45-10 | Final | BX RC |
| Sep. 25 | at Mary Hardin-Baylor * | L, 42-28 | Final | BX |
| Oct. 2 | East Texas Baptist * | W, 49-17 | Final | BX RC P |
| Oct. 9 | at Howard Payne * | W, 56-0 | Final | BX RC |
| Oct. 16 | Sul Ross State * | W, 73-7 | Final | BX RC P |
| Oct. 23 | at Texas Lutheran * | W, 63-17 | Final | BX |
| Oct. 30 | McMurry * | W, 34-13 | Final | BX RC |
| Nov. 13 | at Louisiana College * | L, 44-42 | Final | BX |
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