2010 Schedule Thomas More
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 11-1 | .917 | 7-0 | 1.000 | Lost 1 | 6-0 | 5-1 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 11 | at Hanover | W, 56-12 | Final | BX BX |
| Sep. 18 | at Geneva | W, 36-20 | Final | BX |
| Sep. 25 | Washington and Jefferson * | W, 29-21 | Final | BX RC |
| Oct. 2 | Thiel * | W, 42-3 | Final | BX RC |
| Oct. 9 | at Grove City * | W, 31-9 | Final | BX RC RC |
| Oct. 16 | St. Vincent * | W, 24-6 | Final | BX RC |
| Oct. 23 | at Bethany * | W, 48-14 | Final | BX RC RC |
| Oct. 30 | Westminster (Pa.) * | W, 37-13 | Final | BX RC |
| Nov. 6 | at Waynesburg * | W, 14-10 | Final | BX RC |
| Nov. 13 | Mount St. Joseph | W, 33-0 | Final | BX BX BX RC |
| Nov. 20 | Washington and Lee | W, 42-14 | Final | BX RC |
| Nov. 27 | at Mary Hardin-Baylor | L, 69-7 | Final | BX RC |
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