Through games of Sept. 25, 2022:
| Rank | School (No. 1 votes) | W-L | Points | Prev. |
| 1 | North Central (Ill.) (18) | 3-0 | 612 | 1 |
| 2 | Mount Union (5) | 3-0 | 600 | 3 |
| 3 | UW-Whitewater (1) | 2-1 | 560 | 4 |
| 4 | Mary Hardin-Baylor (1) | 3-1 | 558 | 5 |
| 5 | Trinity (Texas) | 3-0 | 486 | 7 |
| 6 | St. John's | 2-1 | 480 | 2 |
| 7 | Linfield | 2-0 | 449 | 8 |
| 8 | Johns Hopkins | 4-0 | 428 | 9 |
| 9 | UW-La Crosse | 3-0 | 403 | 10 |
| 10 | Hardin-Simmons | 2-1 | 392 | 6 |
| 11 | Wheaton (Ill.) | 2-1 | 366 | 11 |
| 12 | Bethel | 2-1 | 360 | 20 |
| 13 | Ithaca | 3-0 | 336 | 12 |
| 14 | Cortland | 3-0 | 334 | 13 |
| 15 | Delaware Valley | 4-0 | 271 | 14 |
| 16 | UW-Oshkosh | 2-1 | 242 | 15 |
| 17 | UW-River Falls | 2-1 | 235 | 16 |
| 18 | Carnegie Mellon | 4-0 | 209 | 17 |
| 19 | Randolph-Macon | 3-0 | 184 | 18 |
| 20 | Susquehanna | 4-0 | 162 | 21 |
| 21 | Wartburg | 4-0 | 136 | 22 |
| 22 | Albion | 4-0 | 87 | 23 |
| 23 | Central | 2-1 | 38 | 24 |
| 24 | Huntingdon | 3-1 | 37 | -- |
| 25 | DePauw | 4-0 | 22 | -- |
Dropped out: No. 19 Heidelberg; No. 25 Union.
Others receiving votes: Lake Forest 20; George Fox 17; Washington U. 15; UW-Platteville 14; Heidelberg 13; Berry 11; Ursinus 10; Washington & Jefferson 8; Utica 8; John Carroll 7; Muhlenberg 6; Stevenson 3; Case Western Reserve 2; Salisbury 2; Endicott 1; Mount St. Joseph 1.
The D3football.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.