| Date | Away | Home | Time/Status | Links | ||
| Sep. 21 | Chicago | 46 | Elmhurst | 40 | Final | |
| Sep. 21 | Upper Iowa | 6 | Coe | 28 | Final | |
| Sep. 21 | Southern Ore. | 35 | Linfield | 42 | Final | |
| Sep. 21 | Heidelberg | 0 | Muskingum | 19 | Final | |
| Sep. 21 | Concordia-Moorhead | 35 | Bethel | 14 | Final | |
| Sep. 21 | Franklin | 14 | Adrian | 21 | Final | |
| Sep. 21 | Louisiana College | 44 | Sul Ross State | 36 | Final | |
| Sep. 21 | Salisbury | 45 | Methodist | 20 | Final | |
| Sep. 21 | Rose-Hulman | 0 | Wheaton (Ill.) | 49 | Final | BX |
| Sep. 21 | Rowan | 34 | Christopher Newport | 7 | Final | |
| Sep. 21 | Austin | 3 | Mary Hardin-Baylor | 44 | Final | |
| Sep. 21 | Pacific Lutheran | 35 | Chapman | 10 | Final | |
| Sep. 21 | Lakeland | 14 | UW-Oshkosh | 33 | Final | |
| Sep. 21 | Rochester | 28 | Johns Hopkins | 41 | Final | |
| Sep. 21 | St. Thomas | 41 | Hamline | 7 | Final | |
| Sep. 21 | Lebanon Valley | 21 | Widener | 49 | Final | |
| Sep. 21 | Colorado College | 25 | North Central (Ill.) | 30 | Final | |
| Sep. 21 | Hope | 32 | UW-Platteville | 20 | Final | |
| Sep. 21 | Mount Union | 28 | Baldwin-Wallace | 21 | Final | |
| Sep. 21 | Kalamazoo | 53 | Kenyon | 6 | Final | |
| Sep. 21 | New Jersey City | 3 | Western Connecticut | 31 | Final | |
| Sep. 21 | UW-Eau Claire | 14 | UW-Stout | 39 | Final | BX |
| Sep. 21 | Ripon | 43 | Grinnell | 22 | Final | |
| Sep. 21 | RPI | 34 | Coast Guard | 12 | Final | |
| Sep. 21 | Mississippi College | 0 | Howard Payne | 50 | Final | |
| Sep. 21 | Sewanee | 24 | Emory and Henry | 25 | Final | BX |
| Sep. 21 | Anderson | 60 | Concordia-Chicago | 7 | Final | |
| Sep. 21 | Principia | 37 | Macalester | 40 | Final | |
| Sep. 21 | Loras | 7 | Central | 17 | Final | |
| Sep. 21 | Maine Maritime | 7 | Curry | 38 | Final | |
| Sep. 21 | Ohio Northern | 12 | Capital | 47 | Final | |
| Sep. 21 | Susquehanna | 3 | Lycoming | 50 | Final | |
| Sep. 21 | Springfield | 26 | Merchant Marine | 13 | Final | |
| Sep. 21 | Carthage | 49 | Benedictine | 20 | Final | |
| Sep. 21 | Puget Sound | 20 | Claremont-Mudd-Scripps | 30 | Final | |
| Sep. 21 | King's | 50 | Delaware Valley | 14 | Final | |
| Sep. 21 | Lewis and Clark | 20 | Occidental | 21 | Final | |
| Sep. 21 | MIT | 23 | Massachusetts Maritime | 14 | Final | |
| Sep. 21 | Chowan | 0 | Ferrum | 9 | Final | |
| Sep. 21 | Alma | 52 | Manchester | 18 | Final | |
| Sep. 21 | Nichols | 13 | Westfield State | 40 | Final | |
| Sep. 21 | Hiram | 0 | Mount St. Joseph | 51 | Final | |
| Sep. 21 | St. John Fisher | 36 | Norwich | 19 | Final | |
| Sep. 21 | Brockport | 35 | Utica | 0 | Final | |
| Sep. 21 | UW-La Crosse | 17 | Drake | 45 | Final | |
| Sep. 21 | Augsburg | 21 | St. Olaf | 23 | Final | |
| Sep. 21 | Cornell | 14 | Wartburg | 31 | Final | |
| Sep. 21 | Worcester State | 35 | Salve Regina | 6 | Final | |
| Sep. 21 | Grove City | 14 | Defiance | 37 | Final | |
| Sep. 21 | Hartwick | 18 | Ithaca | 19 | Final | |
| Sep. 21 | Mass-Dartmouth | 31 | Bridgewater State | 14 | Final | |
| Sep. 21 | Westminster (Pa.) | 24 | Mansfield | 21 | Final | |
| Sep. 21 | Aurora | 13 | Millikin | 54 | Final | |
| Sep. 21 | Wabash | 44 | Earlham | 7 | Final | |
| Sep. 21 | Blackburn | 13 | Martin Luther | 14 | Final | |
| Sep. 21 | Buffalo State | 7 | Albion | 51 | Final | |
| Sep. 21 | UW-Whitewater | 18 | St. John's | 42 | Final | |
| Sep. 21 | Crown | 13 | Maranatha Baptist | 22 | Final | BX |
| Sep. 21 | Alfred | 16 | St. Lawrence | 13 | Final | |
| Sep. 21 | Albright | 21 | Juniata | 48 | Final | |
| Sep. 21 | Illinois College | 30 | Carroll | 27 | Final | |
| Sep. 21 | Plymouth State | 20 | William Paterson | 30 | Final | |
| Sep. 21 | Oberlin | 11 | Case Western Reserve | 37 | Final | |
| Sep. 21 | Buena Vista | 17 | Simpson | 20 | Final | |
| Sep. 21 | Thomas More | 26 | Shenandoah | 7 | Final | |
| Sep. 21 | Newport News | 20 | Averett | 14 | Final | |
| Sep. 21 | Ursinus | 10 | Franklin and Marshall | 34 | Final | |
| Sep. 21 | Washington and Lee | 31 | Guilford | 30 | Final | BX |
| Sep. 21 | Union | 20 | WPI | 7 | Final | |
| Sep. 21 | Marietta | 27 | Otterbein | 34 | Final | |
| Sep. 21 | Hanover | 31 | DePauw | 21 | Final | BX |
| Sep. 21 | Texas Lutheran | 7 | Hardin-Simmons | 56 | Final | |
| Sep. 21 | Bluffton | 6 | Thiel | 37 | Final | |
| Sep. 21 | Eureka | 8 | North Park | 27 | Final | |
| Sep. 21 | Trinity Bible (N.D.) | 12 | Westminster (Mo.) | 81 | Final | |
| Sep. 21 | Willamette | 28 | Humboldt St. | 42 | Final | |
| Sep. 21 | Muhlenberg | 28 | Dickinson | 21 | Final | |
| Sep. 21 | Luther | 38 | Dubuque | 10 | Final | |
| Sep. 21 | Pomona-Pitzer | 14 | Trinity (Texas) | 66 | Final | |
| Sep. 21 | Rockford | 9 | Northwestern (Minn.) | 19 | Final | BX |
| Sep. 21 | Frostburg State | 27 | Montclair State | 30 | Final | |
| Sep. 21 | Mount Ida | 14 | Stonehill | 45 | Final | |
| Sep. 21 | Kean | 14 | Cortland | 35 | Final | |
| Sep. 21 | Maryville (Tenn.) | 0 | Bridgewater | 42 | Final | |
| Sep. 21 | Gettysburg | 6 | McDaniel | 28 | Final | |
| Sep. 21 | St. Norbert | 28 | Monmouth | 21 | Final | |
| Sep. 21 | McMurry | 21 | East Texas Baptist | 31 | Final | |
| Sep. 21 | Concordia (Wis.) | 24 | Wisconsin Lutheran | 7 | Final | BX |
| Sep. 21 | Wilmington | 0 | John Carroll | 40 | Final | |
| Sep. 21 | Carleton | 14 | Gustavus Adolphus | 48 | Final | |
| Sep. 21 | Centre | 28 | Rhodes | 7 | Final | |
| Sep. 21 | Whitworth | 30 | Menlo | 7 | Final | |
| Sep. 21 | Bethel (Tenn.) | 45 | Greenville | 21 | Final | |
| Sep. 21 | UW-Stevens Point | 29 | Butler | 43 | Final | |
| Sep. 21 | Fitchburg State | 26 | Western New England | 25 | Final | |
| Sep. 21 | Azusa Pacific | 34 | Whittier | 6 | Final | |
| Sep. 21 | Washington U. | 24 | Illinois Wesleyan | 31 | Final | |
| Sep. 21 | Knox | 19 | Lawrence | 0 | Final | |
| Sep. 21 | Denison | 20 | Ohio Wesleyan | 38 | Final | |
| Sep. 21 | St. Ambrose | 21 | Tri-State | 9 | Final | |
| Sep. 21 | Bowdoin | 7 | Williams | 38 | Final | |
| Sep. 21 | Bethany | 28 | Wooster | 38 | Final | |
| Sep. 21 | Colby | 10 | Trinity (Conn.) | 17 | Final | |
| Sep. 21 | Hamilton | 0 | Tufts | 20 | Final | |
| Sep. 21 | Carnegie Mellon | 14 | Randolph-Macon | 17 | Final | |
| Sep. 21 | Bates | 0 | Amherst | 19 | Final | |
| Sep. 21 | Wesleyan | 24 | Middlebury | 21 | Final | |
| Sep. 21 | Lake Forest | 24 | Beloit | 23 | Final |